.cell-lab{--cell-ink:#294553;--cell-muted:#6a7f88;--cell-line:#d8e3e5;--cell-green:#4b8a6b;color:var(--cell-ink);font-size:14px;line-height:1.7;min-width:0}
.cell-lab *{box-sizing:border-box}.cell-lab button,.cell-lab input,.cell-lab select,.cell-lab textarea{font:inherit}.cell-lab button{cursor:pointer;color:var(--cell-ink);border:1px solid var(--cell-line);background:#fff;border-radius:7px;padding:9px 13px;line-height:1.4;min-height:42px;transition:background .12s,border-color .12s}.cell-lab button:hover:not(:disabled){background:#edf5ef;border-color:#a8c7b5}.cell-lab button:disabled{opacity:.5;cursor:default}.cell-lab :is(button,input,select,textarea,a,svg):focus-visible,.cell-lab .cell-organelle:focus-visible{outline:3px solid #638ba9;outline-offset:3px}.cell-lab h2,.cell-lab h3,.cell-lab p{margin:0}.cell-lab h2{font-size:30px;font-weight:500;letter-spacing:-.8px;line-height:1.25}.cell-lab h3{font-size:22px;font-weight:500;line-height:1.3}.cell-lab a{color:#4a7a72;text-underline-offset:3px}.cell-lab button.cell-button-primary{background:#4c7f6a;color:#fff;border-color:#4c7f6a}.cell-lab button.cell-button-primary:hover:not(:disabled){background:#3d6d59}.cell-intro{max-width:970px;color:var(--cell-muted);font-size:14px;line-height:1.9}.cell-intro strong{font-weight:550;color:#526d76}.cell-nav{display:flex;flex-wrap:wrap;gap:12px 29px;padding:21px 0 19px;margin:14px 0 36px;border-bottom:1px solid var(--cell-line);font-size:13px}.cell-nav a{text-decoration:none}.cell-nav a:hover{text-decoration:underline}.cell-lab section{scroll-margin-top:24px}.cell-section-heading{display:flex;align-items:center;justify-content:space-between;gap:22px;margin-bottom:15px}.cell-kicker{display:block;font-size:10px;letter-spacing:1.1px;text-transform:uppercase;color:#81958e;margin-bottom:8px}.cell-muted{color:var(--cell-muted);max-width:950px;margin-bottom:21px!important}.cell-badge{font-size:9px;letter-spacing:.2px;background:#eef3f2;color:#718680;border:1px solid #e0e9e3;border-radius:4px;padding:5px 8px;line-height:1.5;white-space:nowrap}.cell-badge-compute{background:#e7f1ec;color:#628773}.cell-type-switch{display:flex;gap:5px;flex-shrink:0;padding:4px;border:1px solid var(--cell-line);border-radius:9px;background:#f0f4f2}.cell-lab .cell-type-switch button{background:transparent;border-color:transparent;min-height:36px;padding:7px 12px;font-size:12px}.cell-lab .cell-type-switch button[aria-pressed=true]{background:#fff;border-color:#d9e4dd;box-shadow:0 2px 5px #29455308}.cell-structure-grid{display:grid;grid-template-columns:minmax(0,1.22fr) minmax(0,1fr);gap:25px}.cell-map-panel{padding:21px 20px 17px;background:#f3f7f4;border:1px solid #dce5de;border-radius:12px;min-width:0}.cell-map-heading{display:flex;align-items:center;justify-content:space-between;gap:10px;font-size:11px;color:#668377}.cell-map{display:block;width:100%;height:auto;aspect-ratio:3/2;max-height:445px;overflow:hidden;touch-action:none;cursor:grab;margin:15px 0 8px;user-select:none}.cell-map:active{cursor:grabbing}.cell-organelle{cursor:pointer;outline:none}.cell-organelle>*:not(title){transition:filter .12s}.cell-organelle:hover>*:not(title),.cell-organelle:focus-visible>*:not(title){filter:brightness(1.03) drop-shadow(0 0 3px #456a7377)}.cell-organelle-selected>*:not(title){filter:drop-shadow(0 0 3px #446b8fcc)}.cell-organelle-selected>g{filter:drop-shadow(0 0 4px #446b8fbb)}.cell-map-controls{display:flex;align-items:center;gap:7px;flex-wrap:wrap}.cell-lab .cell-map-controls button{min-height:36px;padding:7px 10px;font-size:11px}.cell-lab .cell-map-controls button:is([data-cell-action=zoom-in],[data-cell-action=zoom-out]){min-width:36px;font-size:18px;padding:4px 10px}.cell-map-controls output{font-size:11px;min-width:33px;text-align:center;font-variant-numeric:tabular-nums}.cell-hint{font-size:10px;line-height:1.8;color:#72868e}.cell-map-panel>.cell-hint{margin-top:13px}.cell-detail{border-bottom:1px solid var(--cell-line);padding:16px 0 19px;min-width:0;align-self:start}.cell-detail h3{margin-top:6px}.cell-detail-graphic{margin:17px 0 11px;background:#f7f9fa;border-radius:9px;overflow:hidden}.cell-detail-graphic svg{display:block;width:100%;height:auto;min-height:170px}.cell-detail>p:not(.cell-hint){font-size:13px;line-height:1.85}.cell-detail-structure{margin:11px 0!important;color:#7a8d94;font-size:11px!important}.cell-detail>.cell-hint{font-size:10px}.cell-organelle-list{display:flex;flex-wrap:wrap;gap:8px;margin-top:19px}.cell-lab .cell-organelle-list button{min-height:36px;padding:7px 10px;font-size:11px;display:inline-flex;align-items:center;gap:8px}.cell-organelle-list button>span{display:block;width:9px;height:9px;flex-shrink:0;border-radius:50%;background:var(--cell-organelle-color)}.cell-lab .cell-organelle-list button[aria-pressed=true]{background:#eaf2ee;border-color:#b2ccbc;color:#46735d}.cell-transport,.cell-secretion,.cell-investigation{margin-top:51px;padding-top:30px;border-top:1px solid var(--cell-line)}.cell-transport-grid{display:grid;grid-template-columns:minmax(0,1.6fr) minmax(0,1fr);gap:30px;margin-top:25px}.cell-field{display:flex;flex-direction:column;gap:7px;font-size:11px;color:#637c86}.cell-field input,.cell-field select,.cell-field textarea{width:100%;min-width:0;border:1px solid #d2dfe2;border-radius:6px;padding:9px 10px;background:#fff;color:#3f5d6b;line-height:1.5;min-height:42px}.cell-field textarea{resize:vertical;font-size:12px;min-height:89px;margin-bottom:0}.cell-field input[aria-invalid=true]{border:2px solid #b26854}.cell-mode-field{max-width:620px}.cell-model-description{font-size:12px;color:#6d808a;margin-top:13px!important;line-height:1.8;min-height:45px}.cell-process-diagram{border:1px solid #e0e8e9;border-radius:9px;margin-top:17px;padding:10px 14px;background:#f8fafb}.cell-process-diagram>svg{display:block;width:100%;height:auto}.cell-process-diagram>.cell-hint{margin:0 5px 4px}.cell-transport-readout{display:grid;grid-template-columns:repeat(4,1fr);padding:16px 0;gap:11px}.cell-transport-readout>div{display:flex;flex-direction:column;gap:4px}.cell-transport-readout span{font-size:9px;color:#7c8d98;line-height:1.5}.cell-transport-readout strong{font-size:20px;font-weight:500;letter-spacing:-.5px;font-variant-numeric:tabular-nums}.cell-run-controls{display:flex;align-items:center;gap:9px;flex-wrap:wrap;margin:5px 0 12px}.cell-run-controls button{font-size:11px;padding:9px 12px}.cell-run-controls output{font-size:11px;margin-left:auto;font-variant-numeric:tabular-nums}.cell-parameters{padding:22px;background:#f2f6f3;border-radius:10px;align-self:start;min-width:0}.cell-parameters h3{font-size:19px;margin-bottom:8px}.cell-input-grid{display:grid;grid-template-columns:1fr 1fr;gap:12px;margin-top:16px}.cell-input-grid .cell-field:last-child{grid-column:1/-1}.cell-presets{display:grid;grid-template-columns:1fr 1fr;gap:8px;margin-top:17px}.cell-lab .cell-presets button{font-size:10px;padding:7px 6px;min-height:34px}.cell-parameter-note{font-size:10px;color:#789085;line-height:1.8;margin-top:14px!important}.cell-plots{display:grid;grid-template-columns:1fr 1fr;gap:24px;margin-top:20px}.cell-plots figure{margin:0;border-top:1px solid #dce5e8;padding-top:14px;min-width:0}.cell-plots figcaption{font-size:12px;margin-bottom:3px}.cell-plots svg{display:block;width:100%;height:auto}.cell-model-details{font-size:11px;color:#72858f;border-block:1px solid var(--cell-line);padding:13px 0;margin:8px 0 14px}.cell-model-details summary{cursor:pointer;font-size:12px;color:#5b7a77}.cell-model-details p{margin-top:12px;line-height:1.9}.cell-model-details strong{font-weight:550}.cell-lab .cell-save{font-size:11px;padding:8px 11px;min-height:36px}.cell-secretion>p:not(.cell-hint),.cell-investigation>p:not(.cell-hint):not(.cell-feedback){font-size:12px;color:#6e848f;max-width:900px;line-height:1.9}.cell-pathway{display:grid;grid-template-columns:repeat(6,1fr);gap:9px;list-style:none;margin:24px 0 17px;padding:0;counter-reset:none}.cell-pathway li{min-width:0}.cell-lab .cell-pathway button{width:100%;height:100%;font-size:10px;text-align:left;padding:13px 11px;display:flex;flex-direction:column;align-items:start;gap:9px;background:#f5f7f9}.cell-pathway button>span{border:1px solid #cfdbe1;border-radius:50%;width:23px;height:23px;text-align:center;line-height:21px;font-size:10px;color:#8496a3}.cell-lab .cell-pathway button[aria-current=step]{background:#edf2ee;border-color:#a7c5b1}.cell-pathway button[aria-current=step]>span{background:#6d957b;border-color:#6d957b;color:#fff}.cell-pathway-detail{display:flex;align-items:center;gap:21px;padding:21px 23px;background:#faf6ee;border-left:3px solid #d7bc86;min-height:112px}.cell-pathway-detail strong{font-size:13px;font-weight:550}.cell-pathway-detail p{font-size:12px;color:#8b806a;margin-top:5px;line-height:1.8}.cell-protein-glyph{font-size:17px;letter-spacing:-3px;color:#bb945b;white-space:nowrap;flex-shrink:0}.cell-pathway-controls{display:flex;gap:9px;flex-wrap:wrap;margin:15px 0 10px}.cell-pathway-controls button{font-size:11px}.cell-hypothesis{margin:23px 0 17px;padding:18px 21px;border:1px solid #d5e2df;border-radius:9px;background:#f5f8f5}.cell-hypothesis legend{font-size:12px;padding:0 7px}.cell-hypothesis>label{display:flex;align-items:start;gap:11px;font-size:12px;line-height:1.7;cursor:pointer;margin:10px 0}.cell-hypothesis input{accent-color:#638d73;width:17px;height:17px;flex-shrink:0;margin-top:2px}.cell-hypothesis:disabled>label{opacity:.75;cursor:default}.cell-investigation-actions{display:flex;gap:10px;flex-wrap:wrap;margin:13px 0}.cell-investigation-actions button{font-size:11px}.cell-trials{margin:20px 0 22px;overflow-x:auto}.cell-trials table{border-collapse:collapse;width:100%;font-size:11px;min-width:500px}.cell-trials caption{text-align:left;font-size:12px;margin-bottom:9px}.cell-trials th,.cell-trials td{text-align:left;padding:10px 12px;border-bottom:1px solid #dce5e8;font-variant-numeric:tabular-nums;white-space:nowrap}.cell-trials th{font-weight:500;color:#6a8590;background:#f1f5f6}.cell-trials td{font-size:12px;color:#44616f}.cell-conclusion-field{margin-bottom:18px}.cell-feedback{font-size:12px;line-height:1.9;color:#9c714b;background:#fbf7ee;border-radius:7px;padding:14px 17px;margin-top:15px!important}.cell-feedback:empty{display:none}.cell-feedback.cell-success{color:#4e7b62;background:#edf5ed}.cell-status{font-size:11px;line-height:1.8;color:#5b7f72;min-height:20px;margin-top:20px!important}
@media(max-width:1050px){.cell-structure-grid{gap:20px;grid-template-columns:1.1fr 1fr}.cell-map-heading{flex-wrap:wrap;align-items:start;gap:8px}.cell-transport-grid{gap:20px;grid-template-columns:1.45fr 1fr}.cell-run-controls output{width:100%;margin-left:0}.cell-parameters{padding:18px}.cell-pathway{grid-template-columns:repeat(3,1fr)}.cell-plots{gap:17px}}
@media(max-width:800px){.cell-structure-grid{grid-template-columns:1fr}.cell-detail{padding-top:6px;display:grid;grid-template-columns:1fr 1fr;column-gap:22px}.cell-detail>.cell-kicker,.cell-detail>h3{grid-column:1/-1}.cell-detail-graphic{grid-column:1;grid-row:3/6;margin-bottom:0}.cell-detail>p{grid-column:2}.cell-detail>p:not(.cell-hint){margin-top:15px}.cell-detail>.cell-hint{margin-bottom:8px}.cell-transport-grid{grid-template-columns:1fr}.cell-parameters{display:grid;grid-template-columns:1fr 1fr;column-gap:22px}.cell-parameters h3,.cell-parameters>.cell-hint{grid-column:1}.cell-parameters .cell-input-grid{grid-column:1;grid-row:3/5}.cell-parameters .cell-presets{grid-column:2;grid-row:3}.cell-parameter-note{grid-column:2;grid-row:4}.cell-lab h2{font-size:27px}.cell-section-heading{gap:12px}.cell-transport-readout strong{font-size:22px}.cell-run-controls output{width:auto;margin-left:auto}}
@media(max-width:550px){.cell-lab{font-size:13px}.cell-intro{font-size:12px}.cell-nav{gap:10px 19px;font-size:11px;margin-bottom:25px}.cell-section-heading{align-items:start;flex-wrap:wrap}.cell-section-heading>.cell-badge{margin-top:2px}.cell-lab h2{font-size:25px}.cell-kicker{font-size:9px;letter-spacing:.7px}.cell-type-switch{margin:2px 0 2px}.cell-lab .cell-type-switch button{font-size:11px}.cell-muted{font-size:11px;line-height:1.8}.cell-map-panel{padding:17px 13px 14px}.cell-map-heading{font-size:10px}.cell-map-heading>.cell-badge{font-size:8px;padding:4px 6px}.cell-map{margin:14px 0 7px;min-height:200px}.cell-map-controls{gap:5px}.cell-lab .cell-map-controls button{font-size:10px;padding:7px 8px}.cell-map-controls output{font-size:10px;min-width:29px}.cell-detail{display:block;padding-bottom:17px}.cell-detail h3{font-size:22px}.cell-detail-graphic{margin-top:16px;margin-bottom:14px}.cell-detail-graphic svg{min-height:160px}.cell-detail>p:not(.cell-hint){font-size:12px;margin-top:10px}.cell-detail-structure{font-size:10px!important}.cell-organelle-list{gap:6px}.cell-lab .cell-organelle-list button{font-size:10px;min-height:34px;gap:6px;padding:6px 8px}.cell-transport,.cell-secretion,.cell-investigation{margin-top:35px;padding-top:25px}.cell-field{font-size:11px}.cell-field select{font-size:12px;min-height:46px}.cell-mode-field select{font-size:11px}.cell-model-description{font-size:11px}.cell-process-diagram{padding:8px 7px}.cell-process-diagram>.cell-hint{font-size:9px}.cell-transport-readout{gap:10px;grid-template-columns:1fr 1fr;padding:17px 0}.cell-transport-readout>div{padding-bottom:5px}.cell-transport-readout span{font-size:10px}.cell-transport-readout strong{font-size:23px}.cell-run-controls{gap:7px}.cell-run-controls button{font-size:10px;min-height:40px;padding:9px 10px}.cell-run-controls output{width:100%;margin-left:0;font-size:11px;margin-top:3px}.cell-parameters{display:block;padding:19px 17px}.cell-parameters .cell-input-grid{margin-top:15px;gap:13px}.cell-input-grid input{font-size:15px}.cell-presets{gap:9px;margin-top:20px}.cell-lab .cell-presets button{min-height:40px;font-size:11px}.cell-parameter-note{margin-top:15px!important}.cell-plots{grid-template-columns:1fr;gap:12px;margin-top:18px}.cell-plots figure{padding-top:12px}.cell-plots figcaption{font-size:12px}.cell-hint{font-size:10px}.cell-model-details{font-size:11px}.cell-model-details summary{font-size:11px}.cell-pathway{grid-template-columns:repeat(2,1fr);gap:8px}.cell-lab .cell-pathway button{font-size:11px;padding:13px 12px;flex-direction:row;align-items:center;gap:9px;min-height:75px}.cell-pathway button>span{flex-shrink:0}.cell-pathway-detail{padding:18px 16px;gap:15px;align-items:start}.cell-pathway-detail strong{font-size:12px}.cell-pathway-detail p{font-size:11px}.cell-protein-glyph{font-size:14px;letter-spacing:-3px}.cell-pathway-controls{gap:7px}.cell-pathway-controls button{font-size:10px;min-height:39px;padding:8px 10px}.cell-hypothesis{padding:15px 13px}.cell-hypothesis>label{font-size:11px;gap:9px;margin:13px 0}.cell-investigation-actions{gap:7px}.cell-investigation-actions button{font-size:10px;padding:9px 10px}.cell-trials th,.cell-trials td{padding:10px}.cell-feedback{font-size:11px;padding:13px 14px}.cell-conclusion-field select{font-size:11px}.cell-field textarea{font-size:12px}.cell-status{font-size:10px}}
@media(prefers-reduced-motion:reduce){.cell-lab *{transition:none!important}}
.cell-lab .cell-nav button{background:transparent;border:0;border-radius:0;padding:2px 0;min-height:31px;color:#4a7a72;font-size:13px}.cell-lab .cell-nav button:hover{background:transparent;border-color:transparent;text-decoration:underline;text-underline-offset:3px}
@media(max-width:550px){.cell-lab .cell-nav button{font-size:11px}}